
Curt Connors is a brilliant lead scientist at E.S.U. Labs. He’s happily married to his colleague Martha Connors and together they have a young son named Billy. Connors, who was right handed, lost his right arm during the Gulf War. He wears a prosthetic arm and all seems well, but secretly he’d really like his own arm back. As lizards can grow back severed limbs, Connors hopes to create a formula that would allow human beings to do the same. Secretly, he’s been using himself as a guinea pig. Eventually, he’ll hypo a trained does of (what we’re euphemistically calling) “L-Juice” that does grow back his lost arm. But the mutation process wont end there. It will also transform Connors into the Lizard, a super-strong, bestial were-reptile (complete with deadly teeth, claws, and tail). At first Curt is horrified, but before long his mind will cloud over and he wont remember he ever was Curt Connors.
Voice Actor: Dee Brandley Baker
First Appearence: As Connors: S1, E1 "Survival of the Fittest." As the Lizard: S1, E3, "Natural Selection"
My Favorite Quote:
Martha Connors: Curt, you have to hold on.
Curt Connors: No, you need to hurry. I'm losing Control.


When a merciless corporation stole Adrian Toomes last great invention, the betrayal pushed the old inventor over the edge. Embitter Toomes vowed revenge and converted his Magnetic Air Transport System into a winged flight harness! Now know as the Vulture, the has-been inventor has become an airborne terror. And the only one who can stop him is The Spectacular Spider-Man!
Voice Actor: Robert Englund
First Appearence: S1, E1, "Survival of the Fittest"
My Favorite Quote:
Vulture: You fool! You've doomed us both!
Spider-Man: You so have not been paying attention.


The once timid Dr. Otto Octavius survived a sabotaged experiment that fused four mechanical arms to his body. Now as the egotistical Doctor Octopus, he is driven by his hatred for those who tried to harm him, and “Doc Ock” will attack anyone that stands in his way, even The Spectacular Spider-Man!
Voice Actor: Peter MacNicol
First Appearence: As Otto Octavius: S1, E1, "Survival of the Fittest." As Doc Oct: S1 E8 "Reaction"
My Favorite Quote:
Doc Ock: Lib does not equate to clever Spider-man!
Spidey: Yeah, well the arms to sanity ratio hasn't exactly been established yet.


The experiment that was supposed to bond a cutting edge, silicon armor to Flint Marko was botched, and instead the petty criminal’s entire body was converted into an unforeseen form of living sand. Encouraged by his newfound ability to morph his granulate body into weapons, Marko continues his life of crime as Sandman an unrelenting opponent for The Spectacular Spider-Man.
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Muscle for hire Alex O’Hirn wasn’t the sharpest thug on the street, but he knew a good deal when he saw it. O’Hirn agreed to be permanently bonded to an unbreakable suit on armor strong enough to withstand bullets. Charging into mayhem horn first, this enhanced brut calls himself Rhino, and he’s got a score to settle with The Spectacular Spider-Man!
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The Black Cat is a cat burglar. Stealing is as natural to her as breathing. She counts on stealth and occasionally her stunning looks to get the job done. She tries to get in and out quickly and considers a heist as something of a failure if she has to resort to violence. But better violence than prison, right? So she’s a martial arts expert, who really knows her stuff, because in her extra legal line of work, she needs that edge. She also carries a grappling cable and other devices that facilitate her profession. Her alter-ego, Felicia Hardy, is 19-years-old, flirty, and amoral. She never even met Peter Parker, but Felicia/Black Cat has a real yen for Spider-Man. She has no idea he’s 16 and might be a little freaked out if she found out. She really doesn’t get the whole “Do the Right Thing” obsession, but she does admire his passion. It’s the one quality she seems to lack. Still, she’d much prefer if Spidey and she could become permanent partners-in-crime. For his part, Spidey would much prefer she’d help out with the whole great power/great responsibility gig. But the Peter under the mask is (as usual) smitten and inclined to make allowances.
Voice Actor: Tricia Helfer
First Appearance: S1, E10, "Persona"

The Chameleon, a true master of disguise, is an international theft and industrial spy. He’s an expert mimic and can masquerade as nearly any human being on the planet (within reason he’d be hard pressed to pose as the huge Rhino or the nine year old Billy Connors or the sexy Mary Jane). He strictly operates on a for profit basis, often with clients lined up to pay for his services and the fruits of his labors. He has a team of operatives to help him set up and execute his crimes.
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